Increased Serum Creatine Kinase

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Increased serum creatine kinase.

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NOVEL REAGENTS FOR CREATINE KINASE

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Serum Creatine Kinase Activity in Thyroid Disorders

Introduction Serum creatine kinase (CK) was first used as a diagnostic aid in progressive muscular dystrophy in 1959 by Ebashi et al (1). It has since become an important Clinical marker for muscle damage. The serum CK level in healthy individuals depends on age, race, lean body mass and physical activity (2, 3). Musculoskeletal disorders often accompany thyroid dysfunction. In addition to the ...

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Serum creatine kinase levels in normal females.

Serum creatine kinase levels were determined in 75 girls (age range, one month to 15 years) and 200 normal adult women (age range, 18 to 50 years). The values ranged from 12.5 to 80 IU/1 in girls and 19 to 155 IU/1 in adult females. The SCK level appeared to increase with age from 1 to 15 years, after which the level remained fairly constant. These data should be helpful in the detection of car...

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I studied activation of serum creatine kinase (CK) by sulfhydryl reagents, and the optimum assay conditions.Dithiothreitol and -mercaptoethanol were the best activators. Dithioerythritol, L-cys. teine,glutathione,and mercaptoacetatewere less effective. Over a dithiothreitol concentration range from 0.02 to 2 mmol/liter, enzyme activity increased with increasing dithiothreitol. Activation was ma...

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ژورنال

عنوان ژورنال: Clinical Chemistry

سال: 2014

ISSN: 0009-9147,1530-8561

DOI: 10.1373/clinchem.2013.203547